Last update :
19/11/2024
Antihypertensive   Clonidine hydrochloride  
Oral solution
Capsule injection paper bag
Stability of pharmaceutical preparations Stability of mixtures Factors which affect stability Compatibility References pdf
   Chemical structure  

Oral solution
Stability of pharmaceutical preparations   Oral solution   Stability of pharmaceutical preparations : Clonidine hydrochloride     
Container Origine excipient Temperature Storage Duration of stability References
Glass powder 1 mg
® = ?
Potassium sorbate 300 mg
Potassium citrate 346 mg
Citric acid 200 mg
Sodium saccharin 26 mg
Water for injection >> 100 mL
2-8°C Protect from light
90 Day
4052

Glass powder 2 mg
® = ?
Purified water 50 mL
Potassium sorbate 150 mg
Citric acid >> pH 4-5
Simple syrup >> 100 mL
2-8°C Protect from light
90 Day
4272

Glass powder 2 mg
® = ?
Purified water 50 mL
Citric acid >> pH 4-5
Simple syrup >> 100 mL
2-8°C Protect from light
90 Day
4272

Glass powder 2 mg
® = ?
Purified water 50 mL
Citric acid >> pH 4-5
Simple syrup >> 100 mL
23-27°C Protect from light
90 Day
4272

Glass powder 1 mg
® = ? (Novopharm)
Oral Mix® >> 100 mL
25°C Protect from light
91 Day
3714

Glass powder 1 mg
® = ? (Novopharm)
Oral Mix SF® >> 100 mL
25°C Protect from light
91 Day
3714

Glass powder 1 mg
® = ?
Potassium sorbate 300 mg
Potassium citrate 346 mg
Citric acid 200 mg
Sodium saccharin 26 mg
Water for injection >> 100 mL
25°C Protect from light
30 Day
4052

Glass Medicine bottle for injection 15 µg
® = Medicianz Healthcare
Dextrose 5% >> 30 mL
35°C Protect from light
24 Hour
4353
Level of evidence A+

Glass Medicine bottle for injection 150 µg
® = Medicianz Healthcare
Dextrose 5% >> 30 mL
35°C Protect from light
24 Hour
4353
Level of evidence A+

Glass Medicine bottle for injection 15 µg
® = Medicianz Healthcare
Dextrose 10 % >> 30 mL
35°C Protect from light
24 Hour
4353
Level of evidence A+

Glass Medicine bottle for injection 150 µg
® = Medicianz Healthcare
Dextrose 10 % >> 30 mL
35°C Protect from light
24 Hour
4353
Level of evidence A+

Glass Medicine bottle for injection 15 µg
® = Medicianz Healthcare
NaCl 0.9% >> 30 mL
35°C Protect from light
24 Hour
4353
Level of evidence A+

Glass Medicine bottle for injection 150 µg
® = Medicianz Healthcare
NaCl 0.9% >> 30 mL
35°C Protect from light
24 Hour
4353
Level of evidence A+

Glass tablets 6 mg
Catapres®
Simple syrup >> 60 ml
4°C Protect from light
28 Day
2502

Glass powder 6 mg
Clonidine HCl
Purified water 2 ml
Simple syrup >> 60 ml
4°C Protect from light
28 Day
2502

Glass powder 1 mg
® = ? (Novopharm)
Oral Mix® >> 100 mL
4°C Protect from light
91 Day
3714

Glass powder 1 mg
® = ? (Novopharm)
Oral Mix SF® >> 100 mL
4°C Protect from light
91 Day
3714

Glass Medicine bottle for injection 15 µg
® = Medicianz Healthcare
Dextrose 10 % >> 30 mL
4°C Protect from light
7 Day
4353
Level of evidence A+

Glass Medicine bottle for injection 150 µg
® = Medicianz Healthcare
Dextrose 5% >> 30 mL
4°C Protect from light
7 Day
4353
Level of evidence A+

Glass Medicine bottle for injection 15 µg
® = Medicianz Healthcare
Dextrose 5% >> 30 mL
4°C Protect from light
7 Day
4353
Level of evidence A+

Glass Medicine bottle for injection 150 µg
® = Medicianz Healthcare
Dextrose 10 % >> 30 mL
4°C Protect from light
7 Day
4353
Level of evidence A+

Glass Medicine bottle for injection 15 µg
® = Medicianz Healthcare
NaCl 0.9% >> 30 mL
4°C Protect from light
7 Day
4353
Level of evidence A+

Glass Medicine bottle for injection 150 µg
® = Medicianz Healthcare
NaCl 0.9% >> 30 mL
4°C Protect from light
7 Day
4353
Level of evidence A+

plastic bottle tablets 0,6 mg
® = ? (Actavis)
Simple syrup >> 60 ml
2-8°C Protect from light
35 Day
3844

plastic bottle powder 600 µg
® = ?
Inorpha® >> 60 mL
2-8°C Protect from light
60 Day
4090

plastic bottle powder 15 mg
® = ?
SyrSpend SF PH4® >> 150 mL
2-8°C Protect from light
90 Day
4408

plastic bottle powder 15 mg
® = ?
SyrSpend SF PH4® >> 150 mL
20-25°C Protect from light
90 Day
4408

plastic bottle tablets 1.2 mg
® = Mint Pharmaceutical
Orablend® >> 60 mL
23-27°C Protect from light
90 Day
4648
plastic bottle tablets 1.2 mg
® = Teva
Orablend® >> 60 mL
23-27°C Protect from light
90 Day
4648
plastic bottle powder 5 mg
Clonidine HCl
Citric acid 10.2 g
Sodium phosphate 18.3 g
Simple syrup 200 ml
methylparaben
raspberry flavor 50 mg
Distilled water >> 100 ml
pH= 5
25°C Protect from light
270 Day
3319

plastic bottle powder 1 mg
® = ? (Novopharm)
Oral Mix® >> 100 mL
25°C Protect from light
91 Day
3714

plastic bottle powder 1 mg
® = ? (Novopharm)
Oral Mix SF® >> 100 mL
25°C Protect from light
91 Day
3714

plastic bottle powder 1,6 mg
® = ?
microcrystalline cellulose
Suspendit® >> 80 mL
25°C Protect from light
119 Day
4857
plastic bottle powder 8 mg
® = ?
microcrystalline cellulose
Suspendit® >> 80 mL
25°C Protect from light
182 Day
4857
plastic bottle powder 1 mg
® = ? (Novopharm)
Oral Mix® >> 100 mL
4°C Protect from light
91 Day
3714

plastic bottle powder 1 mg
® = ? (Novopharm)
Oral Mix SF® >> 100 mL
4°C Protect from light
91 Day
3714

plastic bottle powder 1,6 mg
® = ?
microcrystalline cellulose
Suspendit® >> 80 mL
5°C Protect from light
182 Day
4857
plastic bottle powder 8 mg
® = ?
microcrystalline cellulose
Suspendit® >> 80 mL
5°C Protect from light
182 Day
4857
syringe tablets 0.03 mg
®=? Boehringer Ingelheim
Orablend® >> 3 ml
25°C Not specified
91 Day
3649

syringe powder 0.05 mg
® = ? (Novopharm)
Oral Mix® >> 5 mL
25°C Protect from light
91 Day
3714

syringe powder 0.05 mg
® = ? (Novopharm)
Oral Mix SF® >> 5 mL
25°C Protect from light
91 Day
3714

syringe tablets 0.03 mg
®=? Boehringer Ingelheim
Orablend® >> 3 ml
4°C Not specified
91 Day
3649


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