Last update :
07/04/2025
Anticancer drug   Methotrexate sodium  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Artrait Argentina
Bendatrexat Germany
Ebetrex Croatia, Denmark, Finland, Hungary, Iran, Norway, Sweden, Tunisia
Ebetrexate
Emthexat Belgium, Colombia, Denmark, Egypt, Great Britain, Luxembourg, Turkey
Emthexate Greece, Netherlands, Spain
Ledertrexate Belgium, Luxembourg, Mexico, Morocco, Netherlands, Slovenia, Tunisia
Maxtrex
Metex Germany, Norway
Methotrexate France
Metoject Belgium, Canada, Chile, Croatia, Denmark, Finland, France, Great Britain, Hungary, Iceland, Ireland, Mexico, Netherlands, Portugal, Slovenia, Spain, Sweden, Switzerland, Turkey
Metotrexato Argentina, Chile
Trexan Chile, Finland
Trexat Germany

Factors which affect stability   injection   Factors which affect stability : Methotrexate sodium        
References
Storage Light Induces Degradation 1155
1158
3731
Storage Light[ 1 mg/ ml] Induces Degradation 145
Solvent Parenteral nutrition (binary mixture) Induces Degradation 301

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