Last update :
19/11/2024
Anticancer drug   Melphalan  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Alkeran Australia, Austria, Belgium, Brazil, Canada, Chile, Colombia, France, Germany, Great Britain, Greece, Ireland, Italy, Luxembourg, Malaysia, New Zealand, Sweden, Switzerland, United Arab Emirates, United States of America
Egymelan Peru
Eriolan Argentina, Ecuador
Melfalan Argentina, Chile, Ecuador, Germany, Spain
Melfoma Argentina, Peru

Factors which affect stability   injection   Factors which affect stability : Melphalan        
References
Solvent Glucose 5% Induces Degradation 3584
Solvent Sodium chloride 3% Induces Enhanced stability 160
Solvent [Cl-]Increase Induces Enhanced stability 854
Temperature Increase Induces Degradation 160
Temperature 4°C5 mg / ml Induces Precipitation 4189
Concentration Reduced concentration Induces Reduced stability 4701

  Mentions Légales