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Anticancer drug   Fludarabine phosphate  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Acetaflur Mexico
Asoleudox Mexico
Beneflur Mexico, Spain
Fludabin Peru
Fludacel India, Peru
Fludakebir Peru
Fludalym Turkey
Fludara Austria, Belgium, Chile, Colombia, Denmark, Egypt, Finland, France, Germany, Great Britain, Hungary, India, Iran, Ireland, Italy, Luxembourg, Malaysia, Netherlands, New Zealand, Poland, Portugal, Romania, Saudi Arabia, Sweden, Switzerland, United States of America, Venezuela
Fludarabin Iceland, Italy, Norway, Sweden, Switzerland
Fludarabina Argentina, Colombia, Peru, Romania, Spain
Fludarabine Belgium, Canada, Iran, New Zealand, Norway, Switzerland, United States of America
Fludarin India
Fludarosa Argentina
Forclina Peru
Ludabina Chile, Colombia
Mepredin Peru
Naprobin India
Neoflubin Iran
Stability in solutions   injection   Stability in solutions : Fludarabine phosphate     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass Water for Injection 25 mg/ml 25°C Protect from light
16 Day
492

Glass Sodium chloride 0,9% 0,5 mg/ml 2-8°C Protect from light
28 Day
2344
Manufacturer's stability data
Glass Sodium chloride 0,9% 0,5 mg/ml 20-25°C Light
28 Day
2344
Manufacturer's stability data
Glass Glucose 5% 0,4 mg/ml 2-8°C Protect from light
28 Day
2344
Manufacturer's stability data
Glass Glucose 5% 0,4 mg/ml 20-25°C
28 Day
2344
Manufacturer's stability data
Polyvinyl chloride Sodium chloride 0,9% 0,1 & 1,5 mg/ml 2-8°C Protect from light
35 Day
2344
Manufacturer's stability data
Polyvinyl chloride Sodium chloride 0,9% 0,1 & 1,5 mg/ml 20-25°C
35 Day
2344
Manufacturer's stability data
Polyvinyl chloride Glucose 5% 0,1 & 1,5 mg/ml 2-8°C Protect from light
35 Day
2344
Manufacturer's stability data
Polyvinyl chloride Glucose 5% 0,1 & 1,5 mg/ml 20-25°C
35 Day
2344
Manufacturer's stability data
Polyethylene Sodium chloride 0,9% 0,5 mg/ml 2-8°C Protect from light
28 Day
2344
Manufacturer's stability data
Polyethylene Sodium chloride 0,9% 0,5 mg/ml 20-25°C
28 Day
2344
Manufacturer's stability data
Polyethylene Glucose 5% 0,4 mg/ml 2-8°C Protect from light
28 Day
2344
Manufacturer's stability data
Polyethylene Glucose 5% 0,4 mg/ml 20-25°C
28 Day
2344
Manufacturer's stability data
Polypropylene Sodium chloride 0,9% 0,5 mg/ml 2-8°C Protect from light
28 Day
2344
Manufacturer's stability data
Polypropylene Sodium chloride 0,9% 0,5 mg/ml 20-25°C
28 Day
2344
Manufacturer's stability data
Polypropylene Glucose 5% 0,4 mg/ml 2-8°C Protect from light
28 Day
2344
Manufacturer's stability data
Polypropylene Glucose 5% 0,4 mg/ml 20-25°C
28 Day
2344
Manufacturer's stability data
Polyolefine Sodium chloride 0,9% 0,04 >> 1 mg/ml 2-8°C Protect from light
21 Day
3306
Level of evidence A
Polyolefine Sodium chloride 0,9% 0,04 >> 1 mg/ml 25°C With or without light
21 Day
3306
Level of evidence A
Polyolefine Sodium chloride 0,9% 0.15 mg/ml 2-8°C Protect from light
14 Day
3670
Level of evidence A+
Not specified NaCl 0,9% or Glucose 5% 0,04 mg/ml 25°C Protect from light
48 Hour
492

Not specified NaCl 0,9% or Glucose 5% 0,04 mg/ml 4°C Protect from light
48 Hour
492

Not specified NaCl 0,9% or Glucose 5% 1 mg/ml 25°C Protect from light
16 Day
492

  Mentions Légales