Last update :
29/10/2024
Anticancer drug   Doxorubicin hydrochloride  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Adriacept Germany
Adriamycin Australia, Austria, Canada, Denmark, Finland, Norway, United States of America
Adriblastin Austria, Switzerland
Adriblastina Belgium, Brazil, Croatia, Greece, Italy, Poland, Slovenia, Turkey
Adriblastine France, Greece
Adrimedac Germany
Biorub Brazil
Biorubina Poland
Dicladox Argentina
Doxolem Brazil
Doxorubicine France, Switzerland
Doxorubin Belgium, Greece
Farmiblastina Spain
Rastocin Poland
Robodoxo Germany

Factors which affect stability   injection   Factors which affect stability : Doxorubicin hydrochloride        
References
Filtration Nylon Induces Adsorption 167
Storage Light Induces Degradation 847
1284
Storage Light[< 0,5 mg / ml] Induces Degradation 1265
Solvent Parenteral nutrition (with lipids) Induces Degradation 1415
Solvent Parenteral nutrition (binary mixture) Induces Degradation 301
Solvent NaHCO3 Induces Degradation 150
pH pH = 4 Induces Enhanced stability 1160
pH pH >7 Induces Degradation 3645
Concentration Reduction Induces Reduced stability 1897
2256

  Mentions Légales