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Anticancer drug   Daunorubicin hydrochloride  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Cerubidin Denmark, Great Britain, Ireland, Norway, Sweden
Cerubidine Belgium, Canada, Chile, France, Luxembourg, Morocco, Netherlands, Switzerland, Tunisia, Turkey, United States of America
D Blastin Morocco
Daunac Colombia
Daunobin India
Daunoblastin Austria, Germany
Daunoblastina Greece, Hungary, Iran, Italy, Saudi Arabia, Spain, Venezuela
Daunocin India, Malaysia, Peru
Daunogobbi Argentina
Daunomed India, Peru
Daunomycin India
Daunoplus India
Daunorubicin Australia, Canada, Great Britain, New Zealand, United States of America
Daunorubicina Chile, Colombia, Ecuador, Mexico, Peru
Daunorubitec India
Daunoside India
Daunotec India, Venezuela
Daurocina Chile
Epodoxo Peru
Maxidauno Argentina, Ecuador
Oncodaunotec Colombia
Rubilem Mexico
Runabicon Colombia, Mexico
Zuleb Mexico
Stability in solutions   injection   Stability in solutions : Daunorubicin hydrochloride     
Container Solvent Concentration Temperature Storage Duration of stability References
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,016 mg/ml 4°C Protect from light
7 Day
148
Level of evidence D
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,02 mg/ml 22°C Light
48 Hour
1897
Level of evidence D
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 mg/ml -20°C Protect from light
43 Day
686
Level of evidence C
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 mg/ml 22°C Protect from light
8 Day
1897
Level of evidence D
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 mg/ml 25°C Not specified
43 Day
686
Level of evidence C
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 mg/ml 4°C Protect from light
43 Day
686
Level of evidence C
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 mg/ml 4°C Protect from light
8 Day
1897
Level of evidence D
Polyethylene NaCl 0,9% or Glucose 5% 0,02 mg/ml 22°C Light
48 Hour
1897
Level of evidence D
Polyethylene NaCl 0,9% or Glucose 5% 0,02 & 0,1 mg/ml 25°C Protect from light
3 Day
1520
Manufacturer's stability data
Polyethylene NaCl 0,9% or Glucose 5% 0,02 & 0,1 mg/ml 4°C Protect from light
8 Day
1520
Manufacturer's stability data
Polyethylene NaCl 0,9% or Glucose 5% 0,1 mg/ml 22°C Light
8 Day
1897
Level of evidence D
Polypropylene NaCl 0,9% or Glucose 5% 0,1 mg/ml 25°C Protect from light
28 Day
632
Level of evidence C
Polypropylene Glucose 5% 0,0157 mg/ml 25°C With or without light
48 Hour
152
Joker
Polypropylene Glucose 5% 0,0157 mg/ml 4°C With or without light
48 Hour
152
Joker
Polypropylene Ringer’s lactate solution 0,1 mg/ml 25°C Protect from light
28 Day
632
Level of evidence C
Polyolefine NaCl 0,9% or Glucose 5% 0,4 >> 3 mg/ml 22°C Protect from light
14 Day
3438
Level of evidence A+
Polyolefine NaCl 0,9% or Glucose 5% 0,4 >> 3 mg/ml 4°C Protect from light
14 Day
3438
Level of evidence A+
Polypropylen Syringe Water for Injection 2 mg/ml 4°C Protect from light
43 Day
686
Level of evidence C
  Mentions Légales