Last update :
19/11/2024
Diuretic   Spironolactone  
Oral solution
Stability of pharmaceutical preparations Stability of mixtures Factors which affect stability Compatibility References pdf
   Chemical structure  

Oral solution
Stability of pharmaceutical preparations   Oral solution   Stability of pharmaceutical preparations : Spironolactone     
Container Origine excipient Temperature Storage Duration of stability References
Glass powder 100 mg
® = ?
SyrSpend SF PH4® Dry 1,3 g
Water for injection >> 20 mL
18-26°C Protect from light
60 Day
4256

Glass tablets 100 mg
Aldactone®
Water for injection 5 ml
Simple syrup >> 40 ml
19-25°C Protect from light
3 Day
2928

Glass tablets 100 mg
Aldactone®
Water for injection 5 ml
Potassium sorbate 80 mg
Simple syrup >> 40 ml
19-25°C Protect from light
60 Day
2928

Glass tablets 100 mg
Aldactone®
Water for injection 5 ml
Simple syrup >> 40 ml
2-8°C Protect from light
3 Day
2928

Glass tablets 100 mg
Aldactone®
Water for injection 5 ml
Potassium sorbate 80 mg
Simple syrup >> 40 ml
2-8°C Protect from light
60 Day
2928

Glass powder 100 mg
® = ?
SyrSpend SF PH4® Dry 1,3 g
Water for injection >> 20 mL
2-8°C Protect from light
60 Day
4256

Glass tablets 15 mg
Aldactone®
Purified water 3ml
Cherry syrup >>60ml
20-24°C Light
28 Day
2489

Glass tablets 30 mg
Aldactone®
Purified water 3ml
Cherry syrup >>60ml
20-24°C Light
28 Day
2489

Glass tablets 60 mg
Aldactone®
Purified water 3ml
Cherry syrup >>60ml
20-24°C Light
28 Day
2489

Glass tablets 250 mg
Sprironolactone Goldline®
Carboxymethylcellulose 750 mg
Ethanol 2.5 ml
Simple syrup 100 ml
Purified water >> 250 ml
21-23°C Protect from light
90 Day
2534

Glass tablets 500 mg
Aldactone®
Tragacanth powder 1500 mg
Glycerin 2.5 ml
Benzoic acid ?
chloroform water 1.25 ml
Simple syrup 20 ml
Distilled water >> 100 ml
21-25°C Protect from light
28 Day
2556

Glass tablets 15 mg
Aldactone®
Purified water 3ml
Cherry syrup >>60ml
30°C Protect from light
28 Day
2489

Glass tablets 30 mg
Aldactone®
Purified water 3ml
Cherry syrup >>60ml
30°C Protect from light
28 Day
2489

Glass tablets 60 mg
Aldactone®
Purified water 3ml
Cherry syrup >>60ml
30°C Protect from light
28 Day
2489

Glass tablets 15 mg
Aldactone®
Purified water 3ml
Cherry syrup >>60ml
4 °C Protect from light
28 Day
2489

Glass tablets 30 mg
Aldactone®
Purified water 3ml
Cherry syrup >>60ml
4 °C Protect from light
28 Day
2489

Glass tablets 60 mg
Aldactone®
Purified water 3ml
Cherry syrup >>60ml
4 °C Protect from light
28 Day
2489

Glass tablets 250 mg
Sprironolactone Goldline®
Carboxymethylcellulose 750 mg
Ethanol 2.5 ml
Simple syrup 100 ml
Purified water >> 250 ml
4°C Protect from light
90 Day
2534

Glass tablets 500 mg
Aldactone®
Tragacanth powder 1500 mg
Glycerin 2.5 ml
Benzoic acid ?
chloroform water 1.25 ml
Simple syrup 20 ml
Distilled water >> 100 ml
5-7°C Protect from light
62 Day
2556

plastic bottle powder 300 mg
® = ?
SyrSpend SF PH4® >> 150 ml
2-8°C Not specified
90 Day
4177

plastic bottle powder 375 mg
® = ?
SyrSpend SF PH4® >> 150 ml
2-8°C Not specified
90 Day
4177

plastic bottle tablets 3000 mg
®=? (Mylan)
OraPlus® / OraSweet® (1:1) >> 120 ml
25°C Protect from light
60 Day
2441

plastic bottle tablets 3000 mg
®=? (Mylan)
OraPlus® / OraSweet SF® (1:1) >> 120 ml
25°C Protect from light
60 Day
2441

plastic bottle tablets 3000 mg
®=? (Mylan)
Cherry syrup >> 120 ml
25°C Protect from light
60 Day
2441

plastic bottle powder 2579 mg
® = ?
SyrSpend SF PH4® >> 100 mL
25°C Not specified
90 Day
3810

plastic bottle powder 2502 mg
® = ?
SyrSpend SF PH4 Cherry® >> 100 mL
25°C Not specified
90 Day
3810

plastic bottle tablets 3000 mg
®=? (Mylan)
OraPlus® / OraSweet® (1:1) >> 120 ml
5°C Protect from light
60 Day
2441

plastic bottle tablets 3000 mg
®=? (Mylan)
OraPlus® / OraSweet SF® (1:1) >> 120 ml
5°C Protect from light
60 Day
2441

plastic bottle tablets 3000 mg
®=? (Mylan)
Cherry syrup >> 120 ml
5°C Protect from light
60 Day
2441

Not specified powder 250 mg
Ethanol 96% 20 ml
propylene glycol 10 ml
Glycerin 70 ml
19°C Protect from light
120 Day
2559

Not specified powder 25 mg
® = ?
Suspendit® >> 5 mL
25°C Protect from light
180 Day
4000

Not specified tablets 600 mg
®= ?
Carboxymethylcellulose 900 mg
Veegum® 900 mg
methylparaben 120 mg
Propylparaben 24 mg
propylene glycol 1.2 ml
Sorbitol 70% 48 ml
sodium acetate 350 mg
acetic acid 36% 0.67 ml
sodium bisulfite 120 mg
Sodium edetate 120 mg
Sodium saccharin 24 mg
Pineapple aroma
Distilled water >> 120 ml
30°C Protect from light
90 Day
2854

Not specified powder 250 mg
Ethanol 96% 20 ml
propylene glycol 10 ml
Glycerin 70 ml
4°C Protect from light
480 Day
2559

Not specified tablets 600 mg
®= ?
Carboxymethylcellulose 900 mg
Veegum® 900 mg
methylparaben 120 mg
Propylparaben 24 mg
propylene glycol 1.2 ml
Sorbitol 70% 48 ml
sodium acetate 350 mg
acetic acid 36% 0.67 ml
sodium bisulfite 120 mg
Sodium edetate 120 mg
Sodium saccharin 24 mg
Pineapple aroma
Distilled water >> 120 ml
5°C Protect from light
90 Day
2854

Not specified powder 25 mg
® = ?
Suspendit® >> 5 mL
5°C Protect from light
180 Day
4000


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