Last update :
19/11/2024
Antimuscarinic   Benztropine mesylate  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Cogentin Canada, United States of America
Compatibility   injection   Compatibility : Benztropine mesylate              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Benztropine mesylate 1 mg/ml
injection Caffeine 10 mg/ml
None 3964
Compatible
injection Benztropine mesylate 1 mg/ml
injection Chlorpromazine hydrochloride 25 mg/ml
188
Compatible
injection Benztropine mesylate 1 mg/ml
injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Compatible
injection Benztropine mesylate 1 mg/ml
injection Dexmedetomidine 100 µg/ml
4389
Compatible
injection Benztropine mesylate 1 mg/ml
injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 496
Precipitation after 4 hours Incompatible
injection Benztropine mesylate 2 mg/ml
injection Haloperidol lactate 2 mg/ml
229
Immediate precipitation Incompatible
injection Benztropine mesylate 0.5 mg/ml
injection Haloperidol lactate 0,5 >>>5 mg/ml
229
Immediate precipitation Incompatible
injection Benztropine mesylate 1 mg/ml
injection Haloperidol lactate 5 mg/ml
188
Precipitation after 15 minutes Incompatible
injection Benztropine mesylate 0.67 mg/ml
injection Haloperidol lactate 1.67 mg/ml
None 1643
Compatible
injection Benztropine mesylate 0.33 >> 0.67 mg/ml
injection Haloperidol lactate 1.67 >> 3.33 mg/ml
None 1724
Immediate precipitation Incompatible
injection Benztropine mesylate 0.67 & 0.8 mg/ml
injection Lorazepam 0.8 & 1.33 mg/ml
None 1724
Immediate precipitation Incompatible
injection Benztropine mesylate 0.5 >> 0.8 mg/ml
injection Loxapine 10 >> 25 mg/ml
None 1724
Compatible
injection Benztropine mesylate 1 mg/ml
injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
injection Benztropine mesylate 1 mg/ml
injection Tacrolimus 1000 µg/ml
Sodium chloride 0,9% 479

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