Last update :
05/12/2025
Analgesic   Metamizol sodium  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Algi Spain
Algocalmin Romania
Algopyrin Hungary
Andolor Turkey
Devalgin Turkey
Geralgine Turkey
Metamizol Germany
Minalgin Switzerland
Nolotil Spain
Novalgin Austria, Switzerland, Turkey
Novalgina Italy
Novalgine Belgium
Novo-Plan Turkey
Novopyrine Turkey
Pyralgin Poland
References   injection   References : Metamizol sodium  
Type Publication
1685 Journal Müller H-J, Berg J.
Stabilitätsstudie zu metamizol-natrium im PVC-infusionbeutel.
Krankenhauspharmazie 1998 ; 19: 229-234.
2103 Journal Noguera Rodriguez A, Sancho Chust V, Medina Hernandez C, Medina Hernandez MJ, Jimenez Torrez NV.
Estabilidad y compatibilidad del metamizol en jeringa y en mezclas intravenosas.
Farm Hosp 1999 ; 23: 103-108.
2363 Poster M?ller S, Trittler R, Schubert R, von Hornstein W.F, Strehl E.
Morphin-Metamizol mischungen zur kontinuierlichen parenteralen applikation : Sind sie immer inkompatibel?
ADKA Congress 2006
2364 Poster Müller S, Trittler R, Schubert R, Strehl E.
Hydromorphone and dipyrone in PCA devices: Is still a therapy with hydromorphone?
PharmSciFair 2009
2366 Poster M?ller S, Trittler R, Schubert R.
Oxycodon-Metamizol in PCA pumpen : Kompatibel?
ADKA Congress 2009
3372 Journal Hanci V, Ali Kiraz H, Ömür D, Ekin S, Uyan B, Yurtlu B.S.
Precipitation in Gallipoli: Sugammadex / Amiodarone & Sugammadex / Dobutamine & Sugammadex / Protamine.
Rev Bras Anestesiol 2013 ; 63, 1: 163-166.
4130 Journal Koller AK, Krebs S, Dörje F.
Untersuchungen zur Kompatibilität von Clonidin mit häufig eingesetzen Arzneimittel auf Intensivstationen.
Pharmaceutics 2021 , 13, 21.
4490 Journal Koller A.K, Fischer O, Krebs S.
Medication Safety in Intravenous Therapy: A Compatibility Study and Analysis of Reaction Products of Dihydralazine and Metamizole.
Sci Pharm 2020 ; 88, 25
4642 Poster Larossa garcia M, Jimenez-Lozano I, Boix-Montanés A, Mallandrich Miret M, Clemente Bautista M, cabanas Poy M.J., Gorgas Torner
Compatibilidad en Y de atosiban y farmacois habitualmente utilizados en obstetricia.
SEFH Congress (Virtual) October 2021 2021
4664 Journal Harder M, Fiegl-Lechner A, Oberacher H, Horvath U.E.I, Schlager A, Jeske M, Kerndler S, Schüllner F, Bonn G.F, Rainer M.
Stability evaluation of morphine, hydromorphone, metamizole and esketamine containing analgesic mixtures applied for patient-controlled analgesia in hospice and palliative care.
Biomed Chromatogr 2022 ;e5340.
4855 Journal Dettlaff K, Kowalska A, Gostyńska A.
Physical compatibility of colistin with analgesics during simulated Y-site administration.
Am J Hosp Pharm 2024 ;81,13:365-371
5006 Manufacturer SPASFON, solution injectable en ampoule - Résumé des caractéristiques du produit.
TEVA SANTE 2020

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