Monographie - Clonazepam - Stabilis 4.0

Last update :
05/12/2025

Antiepileptic

Clonazepam

injection

Oral solution

Stability in solutions

Stability of mixtures

Factors which affect stability

Compatibility

Route of administration

References

pdf

Chemical structure

Tradename

Tradename

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Clonazepamum	Poland
Kriadex	Mexico
Ravotril	Chile
Rivotril	Colombia, France, Germany, Hungary, Netherlands, New Zealand, Poland, Spain, Switzerland, United Arab Emirates

References

injection

References : Clonazepam

	Type	Publication
939	Journal	Gilbar PJ, Groves CF. Visual compatibility of total parenteral nutrition solution (Synthamin 17 Premix*) with selected drugs during simulated Y-site injection. Aust J Hosp Pharm 1994 ; 24: 167-170.
1189	Journal	Nation RL, Hackett LP, Dusci LJ. Uptake of clonazepam by plastic intravenous infusion bags and administration sets. Am J Hosp Pharm 1983 ; 40: 1692-1693.
1246	Journal	Hooymans PM, Janknegt R, Lohman JJHM. Comparison of clonazepam sorption to polyvinyl chloride-coated and polyethylene-coated tubings. Pharm Weekbl [Sci] 1990 ; 12: 188-189.
1508	Journal	Voirol P, Berger-Gryllaki M, Pannatier A, Eggimann P, Sadeghipour F. Visual compatibility of insulin aspart with intravenous drugs frequently used in ICU. EJHP 2015 ;22:123-124.
2115	Journal	Schneider JJ, Good Ph, Ravenscroft PJ,. Effect of tubing on loss of clonazepam administered by continuous subcutaneous infusion. J Pain Symptom Manage 2006 ; 31, 6: 563-567.
2217	Journal	Guchelaar H.J, Hartog M.E. De stabiliteit van clonazepaminjectievloeistof. Ziekenhuisfarmacie 1997 ; 13, 1: 21-23.
3184	Manufacturer	Hyaluronidase (Hyalase®) - Summary of Product characteristics. CP Pharmaceuticals 2005
3617	Manufacturer	Hyaluronidase (Hyalase®) - Summary of Product Characteristics Wockhardt 2011
3728	Journal	Correard F, Savry A, Gauthier-Villano L, Pisano P, Pourroy B. Visual compatibility of defibrotide with selected drugs during simulated Y-site administration. Am J Health-Syst Pharm 2014 ; 71: 1288-1291.
3823	Journal	Juan E.P, Palau M.M, Cerd? S.A, Rubert M.A, Nicolau B.R. Compatibilité physique de médicaments administrés dans l’unité de soins intensifs Pharmactuel 2015 ; 48, 3 : 146-152.
3976	Journal	Du Repaire T, Vigne P, Guedon A, Gauthier-Villano L, Bertault Peres P, Pourroy B. Visual compatibility of blinatumomab with selected co-administrated drugs during simulated Y-site administration. Am J Health-Syst Pharm 2017 ; 74,16 : 1217-1218
4867	Poster	Dazan D, Aït Taleb S, Laroyenne N, Hamam Y, Conreur L, Paoli-Lombardo R, Primas N, Lamy E, Castera-Ducros C, Curti C et al. Etude des compatibilités entre la nalbuphine et d'autres principes actifs pour optimiser leur administration en service de pédiatrie. CSH (SNPHPU) Congress sept 2024 2024
4972	Manufacturer	RIVOTRIL 1 mg/1 ml, solution à diluer injectable en ampoules - Résumé des caractéristiques du produit. CHEPLAPHARM ARZNEIMITTEL GMBH 2025

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