Last update :
19/11/2024
Immunosuppressant   Tacrolimus  
injection
Eye-drops Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Prograf Australia, Austria, Canada, Chile, Colombia, Denmark, Finland, France, Germany, Great Britain, Greece, Hungary, Iran, Ireland, Italy, Japan, Malaysia, New Zealand, Norway, Poland, Portugal, Romania, Spain, Sweden, Switzerland, United States of America
Prograft Belgium, Luxembourg, Netherlands
Stability in solutions   injection   Stability in solutions : Tacrolimus     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass NaCl 0,9% or Glucose 5% 4 >>> 100 µg/ml 2-8°C Not specified
24 Hour
3626
Manufacturer's stability data

Glass NaCl 0,9% or Glucose 5% 4 >>> 100 µg/ml 25°C Not specified
24 Hour
3626
Manufacturer's stability data

Polyethylene NaCl 0,9% or Glucose 5% 4 >>> 100 µg/ml 2-8°C Not specified
24 Hour
3626
Manufacturer's stability data

Polyethylene NaCl 0,9% or Glucose 5% 4 >>> 100 µg/ml 25°C Not specified
24 Hour
3626
Manufacturer's stability data

Polypropylene NaCl 0,9% or Glucose 5% 4 >>> 100 µg/ml 2-8°C Not specified
24 Hour
3626
Manufacturer's stability data

Polypropylene NaCl 0,9% or Glucose 5% 4 >>> 100 µg/ml 25°C Not specified
24 Hour
3626
Manufacturer's stability data

Polyolefine NaCl 0,9% or Glucose 5% 10 µg/ml 20-25°C Not specified
48 Hour
3842
Level of evidence C

Polyolefine NaCl 0,9% or Glucose 5% 100 µg/ml 20-25°C Not specified
48 Hour
3842
Level of evidence C

Polyolefine Sodium chloride 0,9% 1 µg/ml 20-25°C Not specified
24 Hour
3842
Level of evidence C

Polyolefine Glucose 5% 1 µg/ml 20-25°C Not specified
48 Hour
3842
Level of evidence C

Excel® bag Sodium chloride 0,9% 2 >> 8 µg/ml 23°C Light
9 Day
3915
Level of evidence A+

Excel® bag Sodium chloride 0,9% 2 >> 8 µg/ml 4°C Protect from light
9 Day
3915
Level of evidence A+


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