Last update :
28/04/2024
Analgesic   Methadone hydrochloride  
Injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Eptadone Italy
Ketalgin Switzerland
Mephenon Belgium
Metasedin Spain
Methadone
Physeptone Great Britain
Stability in solutions   Injection   Stability in solutions : Methadone hydrochloride     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass Sodium chloride 0,9% 5 mg/ml 23-27°C Not specified
180 Day
4406
Level of evidence B

Glass Sodium chloride 0,9% 5 mg/ml 5°C Not specified
180 Day
4406
Level of evidence B

Polyvinyl chloride Sodium chloride 0,9% 1 & 2 & 5 mg/ml 25°C Light
28 Day
224
Level of evidence D


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