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29/10/2024
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Anticancer drug   Docetaxel  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Adenex Colombia
Asodocel Argentina
Axogen Chile
Bagotaxel Chile
Bendadocel Germany
Brecasta Chile
Celtere Peru
Daxotel Chile, Colombia, Egypt, Malaysia
Doce NC Germany
Docefrez India, United States of America
Docekebir Argentina
Docetax Iran, Venezuela
Docetaxin Germany
Docewin Morocco
Dolectran Argentina
Donataxel Argentina, Ecuador, Peru
Doxel Turkey, Venezuela
Doxetal Argentina
Doxitax Turkey
Oncodocel Colombia, Peru
Onkotaxel Austria, Colombia
Ribodocel Germany
Santax Turkey
Tadocel Turkey
Taxceus Great Britain
Taxotan Germany
Taxotere Argentina, Australia, Austria, Belgium, Canada, Chile, Colombia, Croatia, Denmark, Ecuador, Egypt, Finland, France, Germany, Great Britain, Greece, Hungary, Iceland, Iran, Italy, Japan, Luxembourg, Malaysia, Mexico, Morocco, Netherlands, New Zealand, Norway, Poland, Portugal, Romania, Saudi Arabia, Spain, Sweden, Switzerland, Thailand, Tunisia, Turkey, United Arab Emirates, United States of America, Venezuela
Texot Argentina
Tolnexa Romania
Zenotere India, Peru
Stability in solutions   injection   Stability in solutions : Docetaxel     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass NaCl 0,9% or Glucose 5% 0,3 & 0,9 mg/ml 25°C Protect from light
28 Day
1660
Level of evidence A
Glass None 10 mg/ml 23°C Light
21 Day
2210
Level of evidence A
Glass None 10 mg/ml 4°C Protect from light
21 Day
2210
Level of evidence A
Glass specific solvent 10 mg/ml 2-8°C Protect from light
28 Day
1660
Level of evidence A
Glass specific solvent 10 mg/ml 25°C Protect from light
28 Day
1660
Level of evidence A
Polyethylene Sodium chloride 0,9% 0,3 & 0,9 mg/ml 25°C Protect from light
28 Day
1660
Level of evidence A
Polyethylene Sodium chloride 0,9% 0,8 mg/ml 5°C Protect from light
7 Day
3163
Level of evidence C
Polyethylene Sodium chloride 0,9% 0.74 mg/ml 23°C Protect from light
8 Hour
2175
Level of evidence A
Polyethylene Sodium chloride 0,9% 0.74 mg/ml 6°C Protect from light
48 Hour
2175
Level of evidence A
Polypropylene Glucose 5% 0,3 & 0,9 mg/ml 25°C Protect from light
28 Day
1660
Level of evidence A
Polyolefine NaCl 0,9% or Glucose 5% < 0,74 mg/ml 2-8°C Not specified
48 Hour
3130
Manufacturer's stability data
Polyolefine NaCl 0,9% or Glucose 5% < 0,74 mg/ml 25°C Not specified
6 Hour
3130
Manufacturer's stability data
Polyolefine NaCl 0,9% or Glucose 5% 0,24 >> 1 mg/ml 20°C Not specified
28 Day
3215
Level of evidence A
Polyolefine NaCl 0,9% or Glucose 5% 0,24 >> 1 mg/ml 5°C Not specified
28 Day
3215
Level of evidence A
Polyolefine NaCl 0,9% or Glucose 5% 0,3 mg/ml 2-8°C Protect from light
56 Day
3195
Level of evidence A+
Polyolefine NaCl 0,9% or Glucose 5% 0,3 mg/ml 25°C Protect from light
56 Day
3195
Level of evidence A+
Polyolefine NaCl 0,9% or Glucose 5% 0,7 mg/ml 2-8°C Protect from light
56 Day
3195
Level of evidence A+
Polyolefine NaCl 0,9% or Glucose 5% 0,7 mg/ml 25°C Protect from light
56 Day
3195
Level of evidence A+
Polyolefine Sodium chloride 0,9% 0,30 mg/ml 25°C Protect from light
28 Day
3804
Level of evidence A
Polyolefine Sodium chloride 0,9% 0,30 mg/ml 4°C Protect from light
28 Day
3804
Level of evidence A
Polyolefine Sodium chloride 0,9% 0.4 & 0.8 mg/ml 23°C Light
35 Day
2210
Level of evidence A
  Mentions Légales