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Cytoprotective   Dexrazoxane hydrochloride  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Cardioxane Austria, Brazil, Chile, Denmark, Ecuador, France, Germany, Great Britain, Hungary, Ireland, Italy, Mexico, Peru, Poland, Spain, Venezuela
Cyrdanax France, Germany
Dexrazoxane Ecuador, United States of America
Dexrazoxano Mexico, Peru
Razox Peru
Razoxane Colombia
Rhianta Mexico
Savene Belgium, Denmark, Finland, France, Germany, Great Britain, Greece, Hungary, Ireland, Italy, Netherlands, Norway, Poland, Romania, Spain, Sweden
Zinecard Canada, United States of America
Zucordex Mexico
Stability in solutions   injection   Stability in solutions : Dexrazoxane hydrochloride     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass Water for Injection 10 mg/ml 25°C Light
8 Hour
3611
Level of evidence B+
Glass Water for Injection 20 mg/ml 2-8°C Protect from light
4 Hour
3581
Manufacturer's stability data
Glass Water for Injection 20 mg/ml 25°C Protect from light
4 Hour
3581
Manufacturer's stability data
Glass NaCl 0,9% or Glucose 5% 1 mg/ml 4°C Protect from light
24 Hour
381
Level of evidence B
Glass NaCl 0,9% or Glucose 5% 1 & 10 mg/ml 22°C With or without light
6 Hour
381
Level of evidence B
Glass NaCl 0,9% or Glucose 5% 10 mg/ml 4°C Protect from light
6 Hour
381
Level of evidence B
Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 mg/ml 25°C Light
24 Hour
3611
Level of evidence B+
Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 mg/ml 4°C Protect from light
24 Hour
381
Level of evidence B
Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 & 10 mg/ml 22°C With or without light
6 Hour
381
Level of evidence B
Polyvinyl chloride NaCl 0,9% or Glucose 5% 3 mg/ml 25°C Light
8 Hour
3611
Level of evidence B+
Polyvinyl chloride Ringer’s lactate solution 1 mg/ml 25°C Light
24 Hour
3611
Level of evidence B+
Polyvinyl chloride Ringer’s lactate solution 3 mg/ml 25°C Light
8 Hour
3611
Level of evidence B+
Polyvinyl chloride Ringer’s lactate solution 4 & 8 mg/ml 25°C Light
8 Hour
2201
Level of evidence B
Polyethylene Ringer’s lactate solution 4 mg/ml 25°C Light
4 Hour
2201
Level of evidence B
Polyethylene Ringer’s lactate solution 8 mg/ml 25°C Light
8 Hour
2201
Level of evidence B
Not specified Glucose 5% 0,1 & 0,5 mg/ml 25°C Light
24 Hour
1949

Not specified Glucose 5% 1 mg/ml 25°C Light
12 Hour
1949

Not specified Ringer’s lactate solution 3 & 4 mg/ml 25°C Not specified
8 Hour
2224

Not specified Ringer’s lactate solution 3 >> 10 mg/ml 25°C Light
4 Hour
3581
Manufacturer's stability data
  Mentions Légales