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19/11/2024
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Sympathomimetic   Norepinephrine bitartrate  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Adine Chile
Arterenol Germany
Biemefrin Turkey
Boguefren Mexico
Cardenor Turkey
Cardiamed Malaysia
Drenorep Peru
Epinor India
Fioritina Argentina
Hyponor Brazil
Levonor Poland
Levophed Belgium, Canada, Chile, Luxembourg, Malaysia, New Zealand, Saudi Arabia, United Arab Emirates, United States of America
Levophrine Egypt
Nadrin India
Naretia Mexico
Nepridar Mexico
Noradren Peru
Noradrenalin Norway
Noradrenaline France, Great Britain, Ireland, Romania, Switzerland, Tunisia
Norages Spain
Norepine Belgium
Pridam Chile, Mexico
Radrenit Mexico
Softamicid Mexico
Steradine Turkey
Tehipren Mexico
Stability in solutions   injection   Stability in solutions : Norepinephrine bitartrate     
Container Solvent Concentration Temperature Storage Duration of stability References
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,004 & 0,008 mg/ml 25°C Light
24 Hour
642
Level of evidence D
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,064 mg/ml 4°C Protect from light
61 Day
3111
Level of evidence B
Polyvinyl chloride Glucose 5% 0,016 & 0,04 mg/ml 5°C Protect from light
30 Day
197
Level of evidence D
Polyvinyl chloride Glucose 5% 0,064 mg/ml 23°C Protect from light
24 Hour
192
Level of evidence B
Polypropylen Syringe Sodium chloride 0,9% 0.01 mg/ml 2-8°C Protect from light
90 Day
4323
Level of evidence C
Polypropylen Syringe Sodium chloride 0,9% 0.1 mg/ml 2-8°C Protect from light
7 Day
3346
Level of evidence C
Polypropylen Syringe Sodium chloride 0,9% 0.1 mg/ml 2-8°C Protect from light
90 Day
4323
Level of evidence C
Polypropylen Syringe Sodium chloride 0,9% 0.2 mg/ml -20°C Protect from light
365 Day
3989
Level of evidence C
Polypropylen Syringe Sodium chloride 0,9% 0.2 mg/ml 5°C Protect from light
365 Day
3989
Level of evidence C
Polypropylen Syringe Glucose 5% 0,5 mg/ml 20-25°C With or without light
48 Hour
4250
Level of evidence A+
Polypropylen Syringe Glucose 5% 1,16 mg/ml 20-25°C With or without light
48 Hour
4250
Level of evidence A+
AT-Closed vial® Sodium chloride 0,9% 0.2 mg/ml -20°C Protect from light
365 Day
3989
Level of evidence C
AT-Closed vial® Sodium chloride 0,9% 0.2 mg/ml 5°C Protect from light
365 Day
3989
Level of evidence C
Not specified Sodium chloride 0,9% 0,064 mg/ml 22-23°C Protect from light
24 Hour
4758
Level of evidence B
  Mentions Légales