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Analgesic   Pethidine hydrochloride  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Aldodan Austria, Iran, Turkey
Alodan Austria, Iran
Cluyer Argentina
Demerol Canada, United States of America, Venezuela
Dolantin Germany
Dolantina Brazil, Spain
Dolantine Belgium, Luxembourg
Dolargan Hungary, Poland
Dolcontral Germany, Poland
Dolosal Tunisia
Meperidina Argentina, Colombia
Meperidine Canada, United States of America
Pethidin Belgium, Germany
Pethidine France, Great Britain, Iceland, Iran, Ireland, Malaysia, New Zealand, Switzerland
Petidin Denmark, Finland, Norway, Sweden
Petidina Chile
Stability of mixtures   injection   Stability of mixtures : Pethidine hydrochloride     
Container Solvent Concentration Compound Temperature Storage Duration of stability References
Glass Water for Injection 25 mg/ml
injection   Pethidine hydrochloride   
injection   Chlorpromazine hydrochloride 6,25 mg/ml
injection   Hydroxyzine dihydrochloride 12,5 mg/ml
25°C
366 Day
Not specified 342
Level of evidence A
Glass None 5,5 mg/ml
injection   Pethidine hydrochloride   
injection   Palonosetron hydrochloride 25 µg/ml
25°C
4 Hour
2196
Level of evidence A+
Polyvinyl chloride Water for Injection 25 mg/ml
injection   Pethidine hydrochloride   
injection   Chlorpromazine hydrochloride 6,25 mg/ml
injection   Hydroxyzine dihydrochloride 12,5 mg/ml
4°C
366 Day
Protect from light 342
Level of evidence A
Polyvinyl chloride NaCl 0,9% or Glucose 5% 7.35 mg/ml
injection   Pethidine hydrochloride   
injection   Metoclopramide hydrochloride 0.15 mg/ml
32°C
48 Hour
Not specified 930
Level of evidence C
Polyvinyl chloride Sodium chloride 0,9% 4 mg/ml
injection   Pethidine hydrochloride   
injection   Ondansetron hydrochloride 0,1 & 1 mg/ml
22°C
31 Day
Not specified 332
Level of evidence A+
Polyvinyl chloride Sodium chloride 0,9% 8 mg/ml
injection   Pethidine hydrochloride   
injection   Clonidine hydrochloride 0,003 mg/ml
25°C
21 Day
Light 2184
Level of evidence D
Polyvinyl chloride Sodium chloride 0,9% 4 mg/ml
injection   Pethidine hydrochloride   
injection   Ondansetron hydrochloride 0,1 & 1 mg/ml
32°C
7 Day
Not specified 332
Level of evidence A+
Polyvinyl chloride Sodium chloride 0,9% 4 mg/ml
injection   Pethidine hydrochloride   
injection   Ondansetron hydrochloride 0,1 & 1 mg/ml
4°C
31 Day
Protect from light 332
Level of evidence A+
Polypropylene Sodium chloride 0,9% 8,33 mg/ml
injection   Pethidine hydrochloride   
injection   Ondansetron hydrochloride 1,33 mg/ml
23°C
24 Hour
Light 815
Level of evidence C+
Polypropylene Sodium chloride 0,9% 8,33 mg/ml
injection   Pethidine hydrochloride   
injection   Ondansetron hydrochloride 1,33 mg/ml
4°C
24 Hour
Protect from light 815
Level of evidence C+
  Mentions Légales