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18/04/2024
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Antibiotic   Co-trimoxazole  
Injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Bactrim Argentina, Brazil, Colombia, France, Italy, Poland, Republic of South Africa, Saudi Arabia, Sweden, Switzerland, Turkey, United Arab Emirates
Bactrimel Chile, Greece, Netherlands, Venezuela
Biseptol Poland, Russian
Cotrim Finland, Germany, Iran
Cotrimoxazol Chile, Portugal
Cotrimoxazole Great Britain
Cotrizol Argentina
Danferane Argentina
Eusaprim Austria, Belgium, Germany, Luxembourg, Sweden
Nopil Switzerland
Novidrine Argentina
Pisatrina Mexico
Septa Canada
Septra Canada
Septrin Chile, Great Britain, Greece, Ireland, Poland, Portugal, Saudi Arabia, Turkey, United Arab Emirates
Soltrim Spain
Spectrex Argentina
Trimexazole Mexico
Stability in solutions   Injection   Stability in solutions : Co-trimoxazole     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass NaCl 0,9% or Glucose 5% 0,64 / 3,2 mg/ml 23°C-25°C Not specified
48 Hour
442
Level of evidence C
Glass NaCl 0,9% or Glucose 5% 1,6 / 8 mg/ml 23°C-25°C Not specified
1 Hour
442
Level of evidence C
Glass Sodium chloride 0,9% 0,6/3,2 mg/ml 23-25°C Not specified
24 Hour
1197
Level of evidence D
Glass Sodium chloride 0,9% 0,8 / 4 mg/ml 23°C-25°C Not specified
14 Hour
442
Level of evidence C
Glass Sodium chloride 0,9% 1,07 / 5,33 mg/ml 23°C-25°C Not specified
2 Hour
442
Level of evidence C
Glass Sodium chloride 0,9% 1,6/8 mg/ml 23-25°C Not specified
24 Hour
1197
Level of evidence D
Glass Glucose 5% 0,6/3,2 mg/ml 23-25°C Not specified
24 Hour
1197
Level of evidence D
Glass Glucose 5% 0,8 / 4 mg/ml 23°C-25°C Not specified
24 Hour
442
Level of evidence C
Glass Glucose 5% 1,07 / 5,33 mg/ml 23°C-25°C Not specified
4 Hour
442
Level of evidence C
Glass Glucose 5% 1,6/8 mg/ml 23-25°C Not specified
24 Hour
1197
Level of evidence D
Glass Ringer’s lactate solution 0,6/3,2 mg/ml 23-25°C Not specified
12 Hour
1197
Level of evidence D
Glass Ringer’s lactate solution 1,6/8 mg/ml 23-25°C Not specified
24 Hour
1197
Level of evidence D
Glass Sodium chloride 0,45% 0,6/3,2 mg/ml 23-25°C Not specified
24 Hour
1197
Level of evidence D
Glass Sodium chloride 0,45% 1,6/8 mg/ml 23-25°C Not specified
24 Hour
1197
Level of evidence D
Polyvinyl chloride Glucose 5% 3.33/0.66 mg/ml 20-22°C Light
4 Hour
4012
Level of evidence A+
Polyvinyl chloride Glucose 5% 4,21/0,84 mg/ml 20-22°C Light
4 Hour
4012
Level of evidence A+
Polyvinyl chloride Glucose 5% 5,71/1,14 mg/ml 20-22°C Light
2 Hour
4012
Level of evidence A+
Polypropylen Syringe None 16/80 mg/ml 18°C-24°C Light
60 Hour
446
Level of evidence C
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