Last update :
19/11/2024
References   References 961  
Type : Journal

Research teams : Birmingham - Dusley Road Hospital
Authors : Barnes AR.
Title : Chemical stabilities of cefuroxime sodium and metronidazole in an admixture for intravenous infusion.
Reference : J Clin Pharm Ther ; 15: 187-196. 1990

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
injectionCefuroxime sodium Antibiotic
Compatible 7,5 mg/ml + injectionMetronidazole 5 mg/ml + None
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionCefuroxime sodium 7,5 mg/ml + None
Stability of mixtures
Polyvinyl chloride None 4°C Protect from light
injection Cefuroxime sodium 7,5 mg/ml
injection Metronidazole 5 mg/ml
7 Day

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