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References   References 96  
Type : Journal
Research teams : Athens - University of Georgia, College of Pharmacy
Authors : Stewart JT, Warren FW, Johnson SM.
Title : Stability of cefuroxime sodium and aminophylline or theophylline.
Reference : Am J Hosp Pharm ; 51: 809-811. 1994
Level of Evidence : 
Level of evidence B+
Physical stability : 
Visual examination Microscopic examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Stability defined as 95% of the initial concentration
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
InjectionAminophylline Various
Compatible 1 & 2 mg/ml + InjectionCefuroxime sodium 7,5 & 15 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 1 & 2 mg/ml + InjectionCefuroxime sodium 7,5 & 15 mg/ml + Sodium chloride 0,45%
Compatible 1 & 2 mg/ml + InjectionCefuroxime sodium 7,5 & 15 mg/ml + NaCl 0,45% Glucose 5%
InjectionCefuroxime sodium Antibiotic
Compatible 7,5 & 15 mg/ml + InjectionAminophylline 1 & 2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 7,5 & 15 mg/ml + InjectionAminophylline 1 & 2 mg/ml + Sodium chloride 0,45%
Compatible 7,5 & 15 mg/ml + InjectionAminophylline 1 & 2 mg/ml + NaCl 0,45% Glucose 5%
Compatible 7,5 & 15 mg/ml + InjectionTheophylline 0,8 mg/ml + Glucose 5%
InjectionTheophylline Various
Compatible 0,8 mg/ml + InjectionCefuroxime sodium 7,5 & 15 mg/ml + Glucose 5%
Stability of mixtures
Glass NaCl 0,9% or Glucose 5% 22°C Light
Injection Aminophylline 1 & 2 mg/ml
Injection Cefuroxime sodium 7,5 & 15 mg/ml
4 Hour
Glass Glucose 5% 22°C Light
Injection Cefuroxime sodium 7,5 & 15 mg/ml
Injection Theophylline 0,8 mg/ml
4 Hour
Glass Sodium chloride 0,45% 22°C Light
Injection Aminophylline 1 & 2 mg/ml
Injection Cefuroxime sodium 7,5 & 15 mg/ml
4 Hour
Glass NaCl 0,45% Glucose 5% 22°C Light
Injection Aminophylline 1 & 2 mg/ml
Injection Cefuroxime sodium 7,5 & 15 mg/ml
4 Hour
  Mentions Légales