Last update :
18/07/2024
References   References 92  
Type : Journal

Research teams : Toledo - College of Pharmacy and Pharmaceutical Sciences, The University of Toledo
Authors : Lee CY, Mauro VF, Alexander KS.
Title : Visual and spectrophotometric determination of compatibility of alteplase and streptokinase with other injectable drugs.
Reference : Am J Hosp Pharm ; 47: 606-608. 1990

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAlteplase Thrombolytic
Incompatible 1 mg/ml + injectionDobutamine hydrochloride 2 mg/ml + Water for Injection
Incompatible 1 mg/ml + injectionDopamine hydrochloride 8 mg/ml + Water for Injection
Incompatible 1 mg/ml + injectionHeparin sodium 100 UI/ml + Water for Injection
Compatible 1 mg/ml + injectionLidocaine hydrochloride 8 mg/ml + Water for Injection
Incompatible 1 mg/ml + injectionNitroglycerin 0.2 mg/ml + Water for Injection
injectionDobutamine hydrochloride Cardiotonic
Incompatible 2 mg/ml + injectionAlteplase 1 mg/ml + Water for Injection
Incompatible 2 mg/ml + injectionStreptokinase 30000 UI/ml + Glucose 5%
injectionDopamine hydrochloride Cardiotonic
Incompatible 8 mg/ml + injectionAlteplase 1 mg/ml + Water for Injection
Compatible 8 mg/ml + injectionStreptokinase 30000 UI/ml + Glucose 5%
injectionHeparin sodium Anticoagulant
Incompatible 100 UI/ml + injectionAlteplase 1 mg/ml + Water for Injection
Compatible 100 UI/ml + injectionStreptokinase 30000 UI/ml + Glucose 5%
injectionLidocaine hydrochloride Local anesthetic
Compatible 8 mg/ml + injectionAlteplase 1 mg/ml + Water for Injection
Compatible 8 mg/ml + injectionStreptokinase 30000 UI/ml + Glucose 5%
injectionNitroglycerin Vasodilator
Incompatible 0.2 mg/ml + injectionAlteplase 1 mg/ml + Water for Injection
Compatible 0.2 mg/ml + injectionStreptokinase 30000 UI/ml + Glucose 5%
injectionStreptokinase Thrombolytic
Incompatible 30000 UI/ml + injectionDobutamine hydrochloride 2 mg/ml + Glucose 5%
Compatible 30000 UI/ml + injectionDopamine hydrochloride 8 mg/ml + Glucose 5%
Compatible 30000 UI/ml + injectionHeparin sodium 100 UI/ml + Glucose 5%
Compatible 30000 UI/ml + injectionLidocaine hydrochloride 8 mg/ml + Glucose 5%
Compatible 30000 UI/ml + injectionNitroglycerin 0.2 mg/ml + Glucose 5%

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