Last update :
03/05/2024
References   References 92  
Type : Journal

Research teams : Toledo - College of Pharmacy and Pharmaceutical Sciences, The University of Toledo
Authors : Lee CY, Mauro VF, Alexander KS.
Title : Visual and spectrophotometric determination of compatibility of alteplase and streptokinase with other injectable drugs.
Reference : Am J Hosp Pharm ; 47: 606-608. 1990

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionAlteplase Thrombolytic
Incompatible 1 mg/ml + InjectionDobutamine hydrochloride 2 mg/ml + Water for Injection
Incompatible 1 mg/ml + InjectionDopamine hydrochloride 8 mg/ml + Water for Injection
Incompatible 1 mg/ml + InjectionHeparin sodium 100 UI/ml + Water for Injection
Compatible 1 mg/ml + InjectionLidocaine hydrochloride 8 mg/ml + Water for Injection
Incompatible 1 mg/ml + InjectionNitroglycerin 0.2 mg/ml + Water for Injection
InjectionDobutamine hydrochloride Cardiotonic
Incompatible 2 mg/ml + InjectionAlteplase 1 mg/ml + Water for Injection
Incompatible 2 mg/ml + InjectionStreptokinase 30000 UI/ml + Glucose 5%
InjectionDopamine hydrochloride Cardiotonic
Incompatible 8 mg/ml + InjectionAlteplase 1 mg/ml + Water for Injection
Compatible 8 mg/ml + InjectionStreptokinase 30000 UI/ml + Glucose 5%
InjectionHeparin sodium Anticoagulant
Incompatible 100 UI/ml + InjectionAlteplase 1 mg/ml + Water for Injection
Compatible 100 UI/ml + InjectionStreptokinase 30000 UI/ml + Glucose 5%
InjectionLidocaine hydrochloride Local anesthetic
Compatible 8 mg/ml + InjectionAlteplase 1 mg/ml + Water for Injection
Compatible 8 mg/ml + InjectionStreptokinase 30000 UI/ml + Glucose 5%
InjectionNitroglycerin Vasodilator
Incompatible 0.2 mg/ml + InjectionAlteplase 1 mg/ml + Water for Injection
Compatible 0.2 mg/ml + InjectionStreptokinase 30000 UI/ml + Glucose 5%
InjectionStreptokinase Thrombolytic
Incompatible 30000 UI/ml + InjectionDobutamine hydrochloride 2 mg/ml + Glucose 5%
Compatible 30000 UI/ml + InjectionDopamine hydrochloride 8 mg/ml + Glucose 5%
Compatible 30000 UI/ml + InjectionHeparin sodium 100 UI/ml + Glucose 5%
Compatible 30000 UI/ml + InjectionLidocaine hydrochloride 8 mg/ml + Glucose 5%
Compatible 30000 UI/ml + InjectionNitroglycerin 0.2 mg/ml + Glucose 5%

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