Last update :
19/11/2024
References   References 895  
Type : Journal

Research teams : Boston - New England Deaconess Hospital
Authors : Yao JDC, Arkin CF, Karchmer AW.
Title : Vancomycin stability in heparin and total parenteral nutrition solutions: novel approach to therapy of central venous catheter-related infections.
Reference : JPEN ; 16: 268-274. 1992

Level of Evidence : 
Biological analysis
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
No comments for the degradation products

List of drugs
injectionHeparin sodium Anticoagulant
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 100 UI/ml 4°C Protect from light
14 Day
Compatible 100 UI/ml + injectionVancomycin hydrochloride 0.025 mg/ml + Sodium chloride 0,9%
injectionVancomycin hydrochloride Antibiotic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0,025 mg/ml 4°C Protect from light
14 Day
Compatible 0.5 & 1 mg/ml + Parenteral nutrition (binary mixture)
Compatible 0.025 mg/ml + injectionHeparin sodium 100 UI/ml + Sodium chloride 0,9%
Stability of mixtures
Polypropylen Syringe Sodium chloride 0,9% 4°C Protect from light
injection Vancomycin hydrochloride 0,025 mg/ml
injection Heparin sodium 100 UI/ml
14 Day

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