Last update :
19/11/2024
References   References 887  
Type : Journal
Web link : https://doi.org/10.1177/106002809703100906

Research teams : Barcelona - Universitat de Barcelona, Facultat de farmacia
Authors : Pujol M, Munoz M, Prat J, Giona V, De Bolos J.
Title : Stability study of epirubicin in NaCl 0.9% injection.
Reference : Ann Pharmacotherapy ; 31: 992-995. 1997

Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Degradation products not observed in real conditions

List of drugs
injectionEpirubicin hydrochloride Anticancer drug
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 2 mg/ml 25°C With or without light
14 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 2 mg/ml 4°C Protect from light
180 Day

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