Last update :
19/11/2024
References   References 842  
Type : Journal

Research teams : Montpellier - Oncopharmacology Laboratory, Val D'Aurelle Cancer Center
Authors : Pinguet F, Favre G, Canal P, Pujol A, Soula G.
Title : Stability of 5-fluorouracil to heat and light.
Reference : J Pharm Clin ; 9: 155-158. 1990

Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed
Degradation products not observed in real conditions

List of drugs
injectionFluorouracil Anticancer drug
Stability in solutions Polyvinyl chloride Glucose 5% 1 & 10 mg/ml 25°C With or without light
72 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 1 & 10 mg/ml 4°C With or without light
72 Hour

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