Last update :
03/05/2024
References   References 816  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/55/5/466

Research teams : Iowa City - University of Iowa, College of Pharmacy
Authors : Kektar VA, Kolling WM, Nardviriyakul N, VanDer Kamp K, Wurster DE.
Title : Stability of undiluted and diluted adenosine at three temperatures in syringes and bags.
Reference : Am J Health-Syst Pharm ; 55: 466-470. 1998

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionAdenosin Vasodilator
Stability in solutions Glass None 3 mg/ml -15°C Protect from light
28 Day
Stability in solutions Glass None 3 mg/ml 25°C Protect from light
7 Day
Stability in solutions Glass None 3 mg/ml 5°C Protect from light
14 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,75 mg/ml -15°C Protect from light
16 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,75 mg/ml 25°C Protect from light
16 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,75 mg/ml 5°C Protect from light
16 Day
Stability in solutions Polyvinyl chloride Ringer’s lactate solution 0,75 mg/ml -15°C Protect from light
14 Day
Stability in solutions Polyvinyl chloride Ringer’s lactate solution 0,75 mg/ml 25°C Protect from light
14 Day
Stability in solutions Polyvinyl chloride Ringer’s lactate solution 0,75 mg/ml 5°C Protect from light
14 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 0,75 mg/ml -15°C Protect from light
16 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 0,75 mg/ml 25°C Protect from light
16 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 0,75 mg/ml 5°C Protect from light
16 Day
Stability in solutions Polypropylen Syringe Ringer’s lactate solution 0,75 mg/ml -15°C Protect from light
14 Day
Stability in solutions Polypropylen Syringe Ringer’s lactate solution 0,75 mg/ml 25°C Protect from light
14 Day
Stability in solutions Polypropylen Syringe Ringer’s lactate solution 0,75 mg/ml 5°C Protect from light
14 Day
Stability in solutions Polypropylen Syringe None 3 mg/ml -15°C Protect from light
14 Day
Stability in solutions Polypropylen Syringe None 3 mg/ml 25°C Protect from light
7 Day
Stability in solutions Polypropylen Syringe None 3 mg/ml 5°C Protect from light
14 Day

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