Type : |
Journal |
|
Research teams : |
Bethesda - National Institutes of Health Clinical Center |
Authors : |
Cradock JC, Kleinmann LM, Rahman A. |
Title : |
Evaluation of some pharmaceutical aspects of intrathecal methotrexate sodium, cytarabine and hydrocortisone sodium succinate. |
Reference : |
Am J Hosp Pharm ; 35: 402-406. 1978 |
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Level of Evidence : |
|
Level of Evidence : |
![Level of evidence C Level of evidence C](./images/Picto.10614.jpg) |
Cytarabine |
![Level of evidence C Level of evidence C](./images/Picto.10614.jpg) |
Methotrexate sodium |
![Level of evidence D Level of evidence D](./images/Picto.10615.jpg) |
Hydrocortisone sodium succinate |
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Physical stability : |
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Chemical stability : |
![Thin Layer Chromatography Thin Layer Chromatography](./images/Picto.10631.jpg) | Cytarabine | ![Stability defined as 95% of the initial concentration Stability defined as 95% of the initial concentration](./images/Picto.10659.jpg) | Cytarabine | ![Thin Layer Chromatography Thin Layer Chromatography](./images/Picto.10631.jpg) | Methotrexate sodium | ![Stability defined as 95% of the initial concentration Stability defined as 95% of the initial concentration](./images/Picto.10659.jpg) | Methotrexate sodium | ![High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV) High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)](./images/Picto.10694.jpg) | Hydrocortisone sodium succinate | ![Stability defined as 90% of the initial concentration Stability defined as 90% of the initial concentration](./images/Picto.10658.jpg) | Hydrocortisone sodium succinate |
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Other methods : |
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Comments : |
Repeatability / reproducibility / standard range: results not provided or results outside specified values | Cytarabine | Repeatability / reproducibility / standard range: results not provided or results outside specified values | Methotrexate sodium | Repeatability / reproducibility / standard range: results not provided or results outside specified values | Hydrocortisone sodium succinate |
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List of drugs
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