Last update :
28/04/2024
References   References 68  
Type : Journal

Research teams : New Orleans - College of Pharmacy, Xavier University of Louisiana
Authors : Das Gupta V, Pramar Y, Bethea C.
Title : Stability of acyclovir sodium in dextrose and sodium chloride injections.
Reference : J Clin Pharm Ther ; 14: 451-456. 1989

Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
Degradation products not observed in real conditions

List of drugs
InjectionAciclovir sodium Antiviral
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 5 mg/ml 25°C Not specified
37 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 5 mg/ml 5°C Protect from light
37 Day

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