Last update :
18/04/2024
References   References 659  
Type : Journal

Research teams : Ottawa - The Ottawa Hospital, department of Pharmacy
Authors : Donnely RF, Yen M.
Title : Epinephrine stability in plastic syringes and glass vials.
Reference : Can J Hosp Pharm ; 49: 62-65. 1996

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionEpinephrine hydrochloride Sympathomimetic
Stability in solutions Glass Water for Injection 100 µg/ml 25°C Protect from light
7 Day
Stability in solutions Glass Water for Injection 100 µg/ml 25°C Protect from light
7 Day
Stability in solutions Glass Water for Injection 700 µg/ml 25°C Protect from light
56 Day
Stability in solutions Glass Water for Injection 700 µg/ml 25°C Protect from light
56 Day
Stability in solutions Polypropylen Syringe Water for Injection 100 µg/ml 25°C Protect from light
7 Day
Stability in solutions Polypropylen Syringe Water for Injection 700 µg/ml 25°C Protect from light
56 Day

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