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References   References 658  
Type : Journal PC : 0.0006830601092896 
Research teams : Houston - M.D.Anderson Cancer Center
Authors : Xu QA, Zhang YP, Trissel LA, Martinez JF.
Title : Stability of busulfan injection admixtures in 5% dextrose injection and 0.9% sodium chloride injection.
Reference : J Oncol Pharm Practice ; 2: 101-105. 1996
Level of Evidence : 
Level of evidence B+
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
No comments for the degradation products
List of drugs
injectionBusulfan Anticancer drug
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 mg/ml 23°C Not specified
4 Hour
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 mg/ml 23°C Not specified
8 Hour
Stability in solutions Polyolefine NaCl 0,9% or Glucose 5% 0,5 mg/ml 23°C Not specified
8 Hour
Stability in solutions Polyolefine Glucose 5% 0,1 mg/ml 23°C Not specified
4 Hour
  Mentions Légales