Last update :
19/11/2024
References   References 656  
Type : Journal

Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Galanti LM, Hecq JD, Vanbeckbergen D, Jamart J.
Title : Long-term stability of cefuroxime and cefazolin sodium in intravenous infusions.
Reference : J Clin Pharm Ther ; 21: 185-189. 1996

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions
Imperfect separation of the internal standard from the product under study or its degradation products, or understudied

List of drugs
injectionCefazolin sodium Antibiotic
Stability in solutions Polyvinyl chloride Glucose 5% 10 mg/ml 4°C Protect from light
30 Day
injectionCefuroxime sodium Antibiotic
Stability in solutions Polyvinyl chloride Glucose 5% 15 mg/ml 4°C Protect from light
11 Day

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