Last update :
19/11/2024
References   References 640  
Type : Journal

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Walker SE, Dranitsaris G.
Title : Stability of reconstituted ceftriaxone in dextrose and saline solutions.
Reference : Can J Hosp Pharm ; 40: 161-166. 1987

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
ultraviolet spectrometry
Other methods : 
PH measurement 
Comments : 
Degradation products detected but not quantified

List of drugs
injectionCeftriaxone disodium Antibiotic
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 40 mg/ml 23°C Not specified
3 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 40 mg/ml 4°C Protect from light
30 Day
Stability in solutions Polyvinyl chloride Glucose 5% 40 mg/ml 23°C Not specified
1 Day
Stability in solutions Polyvinyl chloride Glucose 5% 40 mg/ml 4°C Protect from light
14 Day

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