Last update :
28/04/2024
References   References 628  
Type : Journal

Research teams : Brooklyn - Long Island University, Arnold and Marie Schwarz College of Pharmacy
Authors : Kirschenbaum HL, Aronoff W, Perentesis GP, Piltz GW, Goldberg RJ, Cutie AJ.
Title : Stability of dobutamine hydrochloride in selected large-volume parenterals.
Reference : Am J Hosp Pharm ; 39: 1923-1925. 1982

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Stability indicating capability inadequately assessed

List of drugs
InjectionDobutamine hydrochloride Cardiotonic
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 mg/ml 25°C Not specified
48 Hour
Stability in solutions Polyvinyl chloride Ringer’s lactate solution 1 mg/ml 25°C Not specified
48 Hour
Stability in solutions Polyvinyl chloride NaCl 0,45% Glucose 5% 1 mg/ml 25°C Not specified
48 Hour

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