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References   References 55  
Type : Journal
Research teams : Nottingham - The Boots Company, Formulation Research Group
Authors : Smith A, Bird G.
Title : The compatibility of diazepam with infusion fluids and their containers.
Reference : J Clin Hosp Pharm ; 7: 181-186. 1982
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
injectionDiazepam Anxiolytic
Factors which affect stability Container Polyvinyl chloride Induces Absorption
Stability in solutions Glass NaCl 0,9% or Glucose 5% 0,04 mg/ml 25°C Not specified
48 Hour
Stability in solutions Polyethylene NaCl 0,9% or Glucose 5% 0,04 mg/ml 25°C Not specified
48 Hour
Stability in solutions Polyethylene NaCl 0,9% or Glucose 5% 0,04 mg/ml 5°C Protect from light
48 Hour
  Mentions Légales