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References   References 5119  
Type : Journal
Web link : https://doi.org/ 10.3390/pharmaceutics17101302
Research teams : Murcia - Arrixaca University Hospital, Pharmacy Service
Authors : Ramirez J.C.R, Hamdani I.T, Gazquez L.B, Viney A.C, Alonso Herreros J.M.
Title : Stability Studies of Clonazepam 2.5 mg/mL Oral Solution and 1 mg/mL Parenteral Solution in Pre-Filled Polypropylene Syringes.
Reference : Pharmaceutics ; 17, 1302. 2025
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
injectionClonazepam Antiepileptic
Stability in solutions Polypropylen Syringe None 1 mg/ml 2-8°C Protect from light
30 Day
Stability in solutions Polypropylen Syringe None 1 mg/ml 25°C Light
30 Day
Stability in solutions Polypropylen Syringe None 1 mg/ml 25°C Protect from light
30 Day
Oral solutionClonazepam Antiepileptic
Stability in solutions syringe Commercial Drug product 2,5 mg/ml
Rivotril®
None
2-8°C Protect from light
30 Day
Stability in solutions syringe Commercial Drug product 2,5 mg/ml
Rivotril®
None
25°C Light
30 Day
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