Last update :
26/03/2025
References   References 4914  
Type : Journal
Web link : https://doi.org/10.1007/s40268-024-00496-0

Research teams : Menges - Novartis, Menges, Slovenia
Authors : Borišek R, Mischo A, Foierl T.
Title : In‐Use Physicochemical Stability of Sandoz Rituximab Biosimilar in 0.9% Sodium Chloride Solution After Prolonged Storage at Room Temperature Conditions.
Reference : Drugs R D ; 24: 553–561. 2024

Level of Evidence : 
Level of evidence A+
Physical stability : 
Protein: Size Exclusion Chromatography 
Chemical stability : 
Capillary electrophoresis
Protein: ionic chromatography
Protein: ultraviolet spectrometry
Other methods : 
Protein: biological activity 
Comments : 

List of drugs
injectionRituximab Anticancer drug
Stability in solutions Polyethylene Sodium chloride 0,9% 1 mg/ml 23-27°C Protect from light
30 Day
Biosimilar
Stability in solutions Polyethylene Sodium chloride 0,9% 1 mg/ml 28-32°C Protect from light
14 Day
Biosimilar

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