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References   References 4851  
Type : Journal
Web link : doi:10.1136/ejhpharm-2024-004227
Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Kinet-Poleur A, Colsoul M.L, Catry E, Bihin B, Sneyers B, Hubert J, Jamart J, Soumoy L, Galanti L,Hecq J-D, Closset M.
Title : Long-term stability of esketamine in polypropylene syringes at 5 ± 3°C.
Reference : EJHP 2024
Level of Evidence : 
Level of evidence B+
Physical stability : 
Visual examination Turbidimetry Microscopic examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed
Repeatability / reproducibility / standard range: results not provided or results outside specified values
List of drugs
injectionEsketamine General anesthetic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1 mg/ml 19-25C Not specified
3 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1 mg/ml 2-8°C Not specified
64 Day
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