Last update :
29/10/2024
References   References 4849  
Type : Journal
Web link : https://doi.org/10.3390/ph17060691

Research teams : Paris - Clinical Pharmacy Department, University Hospital Necker-Enfants Malades
Authors : Sebti M, Schweitzer-Chaput A, Cisternino S, Hinterlang M, Ancedy D, Lam S, Auvity S, Cotteret C, Lortholary O, Schlatter J.
Title : Formulation and Stability of a 1% Clarithromycin-Based Topical Skin Cream: A New Option to Treat Buruli Ulcers?
Reference : Pharmaceuticals , 17, 691. 2024

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
OintmentsClarithromycin Antibiotic
Stability in solutions plastic bottle powder 1 g
Zeclar®
Transcutol® 10 g
Ascorbic acid 100 mg
NaOH >> pH 7,2 +/-0,2
Pentravan® >> 100 g
2-8°C Protect from light
90 Day
Stability in solutions plastic bottle powder 1 g
Zeclar®
Transcutol® 10 g
Ascorbic acid 100 mg
NaOH >> pH 7,2 +/-0,2
Pentravan® >> 100 g
22-25°C Protect from light
90 Day
Stability in solutions plastic bottle powder 1 g
Zeclar®
Transcutol® 10 g
Ascorbic acid 100 mg
NaOH >> pH 7,2 +/-0,2
Pentravan® >> 100 g
38-40°C Protect from light
60 Day

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