| Tipo : |
periódico |
| Enlace : |
https://doi.org/10.1016/j.ijpharm.2023.123643 |
|
| Los equipos de investigación : |
Padoue - Department of Pharmaceutical and Pharmacological Sciences, University of Padua |
| Autores : |
Carpanese D, Rossi V, Di Paolo V, Quintieri L, Penna Zuccolotto G, Sebellin J, Saran C, Pipitone F, Miolo G, de Diana E et al. |
| Título : |
Prolonging the stability of cetuximab (Erbitux®) and panitumumab (Vectibix®): An orthogonal assessment of physicochemical, biological and microbiological properties of original opened glass vials and diluted saline preparations. |
| número : |
Int J Pharm ; 649: 123643. 2024 |
|
| Nivel de evidencia : |
|
| La estabilidad física : |
|
| Estabilidad química : |
|
| otros métodos : |
|
| Comentarios : |
| Proteínas: actividad biológica determinada en cultivo celular |
|
Lista de la molécula
Cetuximab
|
 |
 |
 |
 |
5 mg/ml |
2-8°C |
 |
| 180 |
 |
|
|
 |
 |
 |
1,5 & 4 mg/ml |
2-8°C |
 |
| 30 |
 |
|
|
 |
 |
 |
1,5 & 4 mg/ml |
25°C |
 |
| 15 |
 |
|
|
|
Panitumumab
|
 |
 |
 |
 |
20 mg/ml |
2-8°C |
 |
| 180 |
 |
|
|
 |
 |
 |
3 & 6 mg/ml |
2-8°C |
 |
| 30 |
 |
|
|
 |
 |
 |
3 & 6 mg/ml |
25°C |
 |
| 15 |
 |
|
|
|
|