Last update :
16/06/2024
References   References 4773  
Type : Journal
Web link : https://doi.org/10.1016/j.ejps.2023.106464

Research teams : Lyon - Département Pharmacie, Groupement Hospitalier Edouard Herriot, Lyon, France.
Authors : Merienne C, Filali S, Marchand C, Lapras B, Paillet C, Pirot F.
Title : Predictive stability, novel HPLC-MS analysis and semi-automatic compounding process for the emergency implementation of a production line of pancuronium in injectable solution.
Reference : Eur J Pharm Sci ; 187: 106464. 2023

Level of Evidence : 
Level of evidence B+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - mass spectrometry (HPLC-MS)
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
Degradation products identified and quantified

List of drugs
InjectionPancuronium bromide Curarimimetic
Stability in solutions Glass Specific solvent 2 mg/ml 2-8°C Not specified
912 Day

  Mentions Légales