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References   References 4772  
Type : Journal
Web link : https://jpharmsci.org/article/S0022-3549(23)00247-2/fulltext
Research teams : Quebec - Université Laval, Ecole de Pharmacie
Authors : Porlier A, Gagnon P-Y, Chénard V, Michael N-J, Simard C, Drolet B.
Title : Stability of Opened Durvalumab (IMFINZI) Vials. The Beginning of the End of Costly Product Wastage?
Reference : J Pharm Sci ; 112, 9: 2412-2418. 2023
Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry Protein: Size Exclusion Chromatography Protein: Dynamic Light Scattering 
Chemical stability : 
Protein: Peptide mapping
Protein: ionic chromatography
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
List of drugs
InjectionDurvalumab Anticancer drug
Stability in solutions Partially used vials None 50 mg/ml 20-25°C Light
14 Day
Stability in solutions Partially used vials None 50 mg/ml 4°C Protect from light
14 Day
  Mentions Légales