Last update :
08/05/2024
InfoStab
Infostab
List of drugs
List of drugs
Summary lists
Summary lists
Search for compatibilities
Search for compatibilities
Y-site compatibility table
Y-site compatibility table
References
References
Research teams
Research teams
Valistab
Valistab
Poster
Poster
Links
Links
Sponsors
Sponsors
Authors
Authors
User’s guide
User’s guide
Newsletter
Newsletter
References   References 4756  
Type : Journal
Web link : 10.1177/10781552221088020
Research teams : Andover - Pharmaceutical Research and Development, Pfizer Inc
Authors : Weiser S, Burns C, Zartler E.
Title : Physicochemical stability of PF-06439535 (bevacizumab-bvzr; Zirabev®), a bevacizumab biosimilar, under extended in-use conditions.
Reference : J Oncol Pharm Practice ;29, 5: 1032-1043 2022
Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry Protein: Size Exclusion Chromatography Protein: Dynamic Light Scattering 
Chemical stability : 
Protein: Peptide mapping
Protein: ionic chromatography
Capillary electrophoresis
Ultraviolet spectrometry
Other methods : 
PH measurement 
Comments : 
Proteins: biological activity by cell culture
List of drugs
InjectionBevacizumab Anticancer drug
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 1,4 & 16,5 mg/ml 2-8°C Not specified
42 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 1,4 & 16,5 mg/ml 2-8°C Not specified
42 Day
Stability in solutions Ethylene vinyl acetate Sodium chloride 0,9% 1,4 & 16,5 mg/ml 2-8°C Not specified
42 Day
  Mentions Légales