Type : |
Journal |
Web link : |
https://doi.org/10.3390/ pharmaceutics15020309 |
|
Research teams : |
Mainz - University Medical Center, Johannes Gutenberg |
Authors : |
Linxweiler H, Thiesen J, Krämer I. |
Title : |
Physicochemical Stability of Generic Thiotepa Concentrate and Ready-to-Administer Infusion Solutions for Conditioning Treatment. |
Reference : |
Pharmaceutics ,15, 309. 2023 |
|
Level of Evidence : |
|
Physical stability : |
|
Chemical stability : |
|
Other methods : |
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Comments : |
Degradation products detected but not quantified |
|
List of drugs
Thiotepa
|
![Anticancer drug Anticancer drug](./images/Picto.486.jpg) |
![Factors which affect stability Factors which affect stability](./images/Picto.594.jpg) |
![Temperature Temperature](./images/Picto.679.jpg) |
25°C |
![Induces Induces](./images/Picto.659.gif) |
![Reduced stability Reduced stability](./images/Picto.651.gif) |
![Factors which affect stability Factors which affect stability](./images/Picto.594.jpg) |
![Concentration Concentration](./images/Picto.891.jpg) |
|
![Induces Induces](./images/Picto.659.gif) |
![Reduced stability Reduced stability](./images/Picto.651.gif) |
![Stability in solutions Stability in solutions](./images/Picto.591.jpg) |
![Glass Glass](./images/Picto.532.jpg) |
![Water for Injection Water for Injection](./images/Picto.545.gif) |
10 mg/ml |
2-8°C |
![Not specified Not specified](./images/Picto.530.gif) |
14 |
![Day Day](./images/Picto.542.gif) |
|
|
![Stability in solutions Stability in solutions](./images/Picto.591.jpg) |
![Glass Glass](./images/Picto.532.jpg) |
![Water for Injection Water for Injection](./images/Picto.545.gif) |
10 mg/ml |
25°C |
![Light Light](./images/Picto.528.gif) |
1 |
![Day Day](./images/Picto.542.gif) |
|
|
![Stability in solutions Stability in solutions](./images/Picto.591.jpg) |
![Polyolefine Polyolefine](./images/Picto.537.gif) |
![NaCl 0,9% or Glucose 5% NaCl 0,9% or Glucose 5%](./images/Picto.546.gif) |
1 & 2 & 3 mg/ml |
2-8°C |
![Not specified Not specified](./images/Picto.530.gif) |
14 |
![Day Day](./images/Picto.542.gif) |
|
|
![Stability in solutions Stability in solutions](./images/Picto.591.jpg) |
![Polyolefine Polyolefine](./images/Picto.537.gif) |
![Sodium chloride 0,9% Sodium chloride 0,9%](./images/Picto.547.gif) |
1 & 2 & 3 mg/ml |
25°C |
![Light Light](./images/Picto.528.gif) |
1 |
![Day Day](./images/Picto.542.gif) |
|
|
![Stability in solutions Stability in solutions](./images/Picto.591.jpg) |
![Polyolefine Polyolefine](./images/Picto.537.gif) |
![Glucose 5% Glucose 5%](./images/Picto.548.gif) |
1 mg/ml |
25°C |
![Light Light](./images/Picto.528.gif) |
3 |
![Day Day](./images/Picto.542.gif) |
|
|
![Stability in solutions Stability in solutions](./images/Picto.591.jpg) |
![Polyolefine Polyolefine](./images/Picto.537.gif) |
![Glucose 5% Glucose 5%](./images/Picto.548.gif) |
2 mg/ml |
25°C |
![Light Light](./images/Picto.528.gif) |
5 |
![Day Day](./images/Picto.542.gif) |
|
|
![Stability in solutions Stability in solutions](./images/Picto.591.jpg) |
![Polyolefine Polyolefine](./images/Picto.537.gif) |
![Glucose 5% Glucose 5%](./images/Picto.548.gif) |
3 mg/ml |
25°C |
![Light Light](./images/Picto.528.gif) |
7 |
![Day Day](./images/Picto.542.gif) |
|
|
|
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