Last update :
28/02/2024
References   References 4737  
Type : Journal
Web link : https://doi.org/10.1177/001857872211257

Research teams : Aurora - Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado
Authors : Van Matre E.T, Rice P.J, Wempe M.F, Lyda C, Kiser T.H.
Title : Extended Stability of Isoproterenol Hydrochloride Injection in Polyvinyl Chloride Bags Stored in Amber Ultraviolet Light Blocking Bags.
Reference : Hosp Pharm ; 58, 2/ 183-187. 2023

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - mass spectrometry (HPLC-MS)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point

List of drugs
InjectionIsoprenaline hydrochloride Beta-stimulant
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,004 mg/ml 23-25°C Protect from light
30 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,004 mg/ml 3-5°C Protect from light
90 Day

  Mentions Légales