Last update :
19/11/2024
References   References 4635  
Type : Journal
Web link : https://doi.org/10.1515/pthp-2021-0005

Research teams : Mainz - University Medical Center, Johannes Gutenberg
Authors : Mohr A, Erdnüß F, Krämer I.
Title : Physicochemical stability of human insulin 1 I.U./mL infusion solution in 50 mL polypropylene syringes.
Reference : Pharmaceutical Technology in Hospital Pharmacy ; 6(1): 20210005. 2021

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
injectionInsulin Glucose-lowering
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1 UI/ml 2-8°C Protect from light
21 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1 UI/ml 20-25°C Light
48 Hour

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