Last update :
06/12/2021
References   References 4618  
Type : Journal
Web link : http://dx.doi.org/10.1136/ejhpharm-2021-002935

Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : Loeuille G, Vigneron J, D'Huart E, Charmillon A, Demoré B.
Title : Physicochemical stability of cefiderocol, a novel siderophore cephalosporin, in syringes at 62.5 mg/mL for continuous administration in intensive care units.
Reference : EJHP 2021

Level of Evidence : 
Level of evidence C+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionCefiderocol sulfate tosylate Antibiotic
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 62,5 mg/mL 25°C Light
12 Hour

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