Last update :
06/12/2021
References   References 4607  
Type : Journal
Web link : 10.4212/cjhp.v74i3.3150

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Walker SE, Sachedina H, Bichar K.
Title : Stability of Compounded Clozapine 25 mg/mL and 50 mg/mL Suspensions in Plastic Bottles.
Reference : Can J Hosp Pharm ;74(3):227-34 2021

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
Oral solutionClozapine Neuroleptic
Stability in solutions Plastic bottle Tablets 3000 mg
Clozarine ®
Methylcellulose 1% / Simple syrup (1:1) >> 120 mL
20-25°C Protect from light
120 Day
Stability in solutions Plastic bottle Tablets 6000 mg
Clozarine ®
Methylcellulose 1% / Simple syrup (1:1) >> 120 mL
20-25°C Protect from light
120 Day
Stability in solutions Plastic bottle Tablets 3000 mg
Clozarine ®
Methylcellulose 1% / Simple syrup (1:1) >> 120 mL
4°C Protect from light
120 Day
Stability in solutions Plastic bottle Tablets 6000 mg
Clozarine ®
Methylcellulose 1% / Simple syrup (1:1) >> 120 mL
4°C Protect from light
120 Day

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