Last update :
15/10/2021
References   References 4583  
Type : Journal
Web link : https://ijpc.com/Abstracts/Abstract.cfm?ABS=4929

Research teams : San Francisco - Genentech, Inc
Authors : Hui A, Yin J, Liu W, Zheng K.
Title : Prolonged In-use Stability of Diluted Atezolizumab in Commercial Intravenous Bags
Reference : Int J Pharm Compound ;25,3:246-257 2021

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry Particle counting Size Exclusion Chromatography 
Chemical stability : 
Protein: ionic chromatography
Capillary electrophoresis
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionAtezolizumab Anticancer drug
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 2,4 >> 16,8 mg/ml 2-8°C Protect from light
90 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 2,4 >> 16,8 mg/ml 30°C Light
24 Hour
Stability in solutions Polyolefine Sodium chloride 0,9% 2,4 >> 16,8 mg/ml 2-8°C Protect from light
90 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 2,4 >> 16,8 mg/ml 30°C Light
24 Hour

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