Last update :
06/12/2021
References   References 4573  
Type : Journal
Web link : https://doi.org/10.1093/ajhp/zxab071

Research teams : Bordeaux - Université Bordeaux 2, UFR Pharmacie, Laboratoire de Chimie Analytique
Authors : Legeron R, Bougueon G, Berroneau A, De-Germay S, Bernadou JM, Djabarouti S, Crauste-Manciet S, Xuereb F.
Title : Long-term physicochemical stability of acyclovir 5 mg/mL solution stored in polypropylene bags as a simulated hospital stock preparation.
Reference : Am J Health-Syst Pharm ;78, 9:806–812, 2021

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionAciclovir sodium Antiviral
Stability in solutions Polypropylene Sodium chloride 0,9% 5 mg/ml 2-8°C Not specified
63 Day

  Mentions Légales