Last update :
18/06/2021
References   References 4568  
Type : Journal
Web link : https://doi.org/10.1080/1120009X.2021.1906037

Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Closset M,Onorati S, Colsoul M.L,Goderniaux N,Bihin B, Jamart J, Soumoy L, Hecq J.D, Odou P, Galanti L.
Title : Long-term physico-chemical stability of 5-fluorouracile at standardised rounded doses (SRD) in MyFuser® portable infusion pump.
Reference : Journal of Chemotherapy 2021

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination Microscopic examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed

List of drugs
InjectionFluorouracil Anticancer drug
Stability in solutions Elastomer Sodium chloride 0,9% 35 mg/ml 21-25°C Light
28 Day
Stability in solutions Elastomer Sodium chloride 0,9% 35 mg/ml 30°C Light
3 Day
Stability in solutions Elastomer Sodium chloride 0,9% 44 mg/ml 21-25°C Light
28 Day
Stability in solutions Elastomer Sodium chloride 0,9% 44 mg/ml 30°C Light
3 Day

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