Last update :
19/11/2024
References   References 456  
Type : Journal

Research teams : Oklahoma City - University of Oklahoma Health Sciences Center, College of Pharmacy
Authors : Tu YH, Allen LV, Wang DP.
Title : Stability of papaverine hydrochloride and phentolamine mesylate in injectable mixtures.
Reference : Am J Hosp Pharm ; 44: 2524-2527. 1987

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 

List of drugs
injectionPapaverine hydrochloride Vasodilator
Compatible 30 mg/ml + injectionPhentolamine mesylate 0.5 mg/ml + None
injectionPhentolamine mesylate Vasodilator
Compatible 0.5 mg/ml + injectionPapaverine hydrochloride 30 mg/ml + None
Stability of mixtures
Glass None 25°C Not specified
injection Papaverine hydrochloride 30 mg/ml
injection Phentolamine mesylate 0,5 mg/ml
30 Day
Glass None 5°C Protect from light
injection Papaverine hydrochloride 30 mg/ml
injection Phentolamine mesylate 0,5 mg/ml
30 Day

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