Last update :
19/11/2024
References   References 454  
Type : Journal

Research teams : Pittsburgh - School of Pharmacy, University of Pittsburgh
Authors : Ptachcinski RJ, Logue LW, Burckart GJ, Venkataramanan R.
Title : Stability and availability of cyclosporine in 5% dextrose injection or 0.9% sodium chloride injection.
Reference : Am J Hosp Pharm ; 43: 94-97. 1986

Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
No visual inspection
Stability indicating capability inadequately assessed

List of drugs
injectionCiclosporin Immunosuppressant
Factors which affect stability Container Polyvinyl chloride Induces Adsorption
Stability in solutions Glass Sodium chloride 0,9% 2 mg/ml 24°C With or without light
12 Hour
Stability in solutions Glass Glucose 5% 2 mg/ml 24°C With or without light
24 Hour

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